Florence County, SC Real Estate Search

Florence County, SC 4 Bedroom Homes for Sale

Our website features the best real estate search for 4 bedroom homes available in Florence County, SC and surrounding areas. It is the only site you will ever need! It is easy-to-use and updated by the official REALTOR®’s database every 15 minutes. 

You can save searches, and get daily email alerts of new listings, price changes, sold data, and market reports. Our Interactive Map Search allows you to view properties on a map or refine your search by drawing the boundaries around the area you desire.

Curious about what’s happening in the Florence County, SC real estate market? Sign up for a  Florence County, SC Real Estate Market Report to see what’s active, under contract, and sold!

Considering selling or refinancing your home? Get an INSTANT property valuation now!

Newest Florence County, SC 4 Bedroom Homes for Sale

1409 Fairfax Rd., Florence
$550,000
4 Beds ⋅ 5 Baths ⋅ 2626913 MLS
1409 Fairfax Rd is a residence with a functional layout and comfortable living spaces throughout. The kitchen features stainless steel appliances, a peninsula, ample counter space, and white cabinetry, creating a fully equipped space for cooking and entertaining. A brick fireplace anchors the main living area, adding warmth and ambiance to the central gathering space. A dining room with a chandelier and a wood-paneled den add flexible living space. The bedrooms include ceiling fans, and one features built-in shelving and a fireplace. A bathroom features a separate tub and shower. A rear deck extends the living space outdoors, creating ample room for relaxation and entertaining. This residence combines practical design with comfortable living spaces, delivering functional amenities throughout every room.

1409 Fairfax Rd., Florence

Listing courtesy of Listing Agent: Suha Kazmi () from Listing Office: Opendoor Brokerage LLC.
812 Quail Dr., Pamplico
$279,900
4 Beds ⋅ 3 Baths ⋅ 2626175 MLS
Spacious 2 Story Home • Approx. 2,800± Sq Ft • Beautiful Residential Setting Discover comfort, space, and classic Southern charm in this two-story brick home offering approximately 2,800± square feet of living area. Located in the community of Pamplico, this property provides an ideal blend of privacy, convenience, and timeless design on approximately 1.3 acres. • Approx. 2,800± sq ft of living space • Two-story layout with multiple living areas • Brick fireplace, built-ins, and traditional architectural details • Large kitchen with abundant cabinetry and natural light • Multiple bedrooms and baths offering flexibility for family, guests, or home office needs • Sunroom / enclosed porch providing additional relaxation or entertainment space • Spacious yard with mature trees and room for outdoor enjoyment • Carport and driveway with ample parking • Two Outbuildings / storage structures perfect for tools, hobbies, or equipment The property includes a generous yard with shade trees, a fenced area, and multiple exterior structures ideal for storage or workshop use. A covered carport and wide driveway offer convenience, while the surrounding greenery creates a peaceful, private setting. 812 Quail Drive sits in a Pamplico neighborhood just minutes from schools, local shops, and Highway 51. Florence is a short drive away, making this home an excellent option for those seeking space and comfort without sacrificing accessibility.

812 Quail Dr., Pamplico

Listing courtesy of Listing Agent: Karon Epps (karon@emerealty.com) from Listing Office: Epps Miles Eaddy Realty Inc.
601 Rivers St., Lake City
$299,000
4 Beds ⋅ 3 Baths ⋅ 2625637 MLS
Welcome home to this spacious 2,800 square foot, two-story brick residence offering the perfect blend of comfort, functionality, and classic Southern charm. With 4 bedrooms, 2.5 bathrooms, and multiple living spaces, this home is ideal for growing families or anyone who loves to entertain. Step through the welcoming foyer into a thoughtfully designed floor plan featuring a formal living room, elegant formal dining room, and a cozy den with a fireplace equipped with gas logs, creating the perfect gathering space year-round. The well-appointed kitchen is designed for both everyday living and entertaining, featuring: • Solid surface countertops • Attractive subway tile backsplash • Large walk-in pantry • Refrigerator, range, and dishwasher included Retreat to the spacious primary suite, highlighted by a beautiful tray ceiling and a private en suite bath designed for comfort and relaxation. Additional features include: • 4 Bedrooms • 2 Full Baths and 1 Half Bath • Double Attached Garage • Covered Rear Patio • Fenced Backyard • Two-Story Brick Construction • Multiple Living and Entertaining Areas Enjoy outdoor living. Fenced backyard for gardening or weekend gatherings. The covered rear patio provides a comfortable space to relax and enjoy the outdoors in any season.

601 Rivers St., Lake City

Listing courtesy of Listing Agent: Karon Epps (karon@emerealty.com) from Listing Office: Epps Miles Eaddy Realty Inc.
1307 Fairlane Dr, Florence
$285,000
4 Beds ⋅ 2 Baths ⋅ 2624661 MLS
Welcome home to this spacious 4-bedroom, 2-bath all-brick home situated on a large lot in the heart of the City of Florence—with NO HOA! Offering plenty of square footage at an affordable price, this home is filled with character, natural light and endless potential. Inside, you’ll find original hardwood floors, wood-look tile, updated bathrooms and freshly painted interiors. With both a formal living room and a separate family room, there’s plenty of space to spread out and entertain. The home also features a separate dining room, a wood-burning fireplace and an oversized laundry room offering excellent additional storage. Outside, enjoy beautiful curb appeal, mature landscaping and a large, fully fenced backyard with plenty of room for pets, play or entertaining. A spacious back patio with pergola creates the perfect spot for outdoor gatherings, while both attached and detached storage sheds provide added convenience. The property also offers plenty of parking. Conveniently located close to everything Florence has to offer, this home is a fantastic opportunity for buyers looking for space, character and value. With a little TLC and your own personal touches, you can truly make this home your own!

1307 Fairlane Dr, Florence

Listing courtesy of Listing Agent: Prime Group Team () from Listing Office: The Litchfield Company Real Estate-PrinceCrk.
3325 Shadow Creek Dr., Florence
$589,900
4 Beds ⋅ 3 Baths ⋅ 2621093 MLS
This beautiful custom 5/3 home offers approx. 3200 sq ft, 2 Car garage, spacious kitchen for hosting or every day dinners, luxurious landscaping including an irrigation system fed by its own well pump, and sits on approximately .50 acres. This home offers a chance to truly create your dream home, Fencible back yard, Pools allowed, and low HOA. 10-15 Minutes from downtown, dining, shopping, and other local attractions!

3325 Shadow Creek Dr., Florence

Listing courtesy of Listing Agent: Kaleb Huggins () from Listing Office: Century 21 Palms Realty.
712 Bellemeade Circle, Florence
$396,000
4 Beds ⋅ 3 Baths ⋅ 2620297 MLS
712 Bellemeade Cir is a two-story Florence single-family home built in 2016 on a 6,049-square-foot lot. The kitchen features a granite-topped center island, white cabinetry, stainless steel appliances, and hardwood flooring that opens to the living and dining areas. The main living space includes a fireplace and hardwood flooring, with large windows drawing in natural light. The primary bathroom offers a separate soaking tub, a glass-enclosed shower, and a double vanity, and the home provides four bedrooms and three full bathrooms across two levels, along with a walk-in closet. The fully fenced backyard overlooks a pond and provides room for outdoor use. A two-car garage adds covered parking, and the home sits within the Wessex Homeowners Association with city water and sewer service.

712 Bellemeade Circle, Florence

Listing courtesy of Listing Agent: Thomas Shoupe () from Listing Office: Opendoor Brokerage LLC.
948 Whispering Pines Rd., Johnsonville
$599,000
4 Beds ⋅ 2 Baths ⋅ 2620235 MLS
The one that you have been waiting for. 4 bedroom 2 full bath out of town limits of Johnsonville on Whispering Pines Road. Home has town water and well and 38.1 acres of land which gives you all the room to expand, hunt, or use for recreation. Living room, dining room, and den plus the beds and baths and laundry room. 2 car carport with attached utility room. There are 2 additional storage buildings and sheds out back so bring all your toys and get ready to live a peaceful life away from the hustle and bustle of cities and towns. Septic tank. Johnsonville School District 5.

948 Whispering Pines Rd., Johnsonville

Listing courtesy of Listing Agent: Doug Joy (Cell: 843-344-2706) from Listing Office: RE/MAX Executive.
840 Thunderbird Dr, Florence
$309,000
4 Beds ⋅ 2 Baths ⋅ 2618641 MLS
Welcome to 840 Thunderbird Dr., where thoughtful updates and timeless charm come together in this move-in-ready home. Nestled in the desirable Oakdale neighborhood, this beautifully updated property offers a peaceful, established setting while remaining conveniently close to shopping, dining, schools, and everyday amenities. With 3 bedrooms, 2 baths on the main floor, and a large bonus room or 4th bedroom upstairs. The kitchen features white quartz countertops, stainless steel appliances, and newly painted black cabinetry, creating a timeless, high-contrast design. Luxury vinyl plank flooring flows throughout the main living areas, while the bedrooms offer comfortable carpeting. The updated fireplace with its painted surround and natural wood mantel adds warmth and character, creating an inviting focal point in the living room, complete with gas logs. Both bathrooms have been updated, including a renovated primary shower and refreshed guest bath. Some major improvements include a newer roof, HVAC system, updated ductwork, hot water heater, and a spacious rear deck overlooking the backyard. Opportunities to own in the Oakdale neighborhood are few and far between, making this a wonderful chance to enjoy its peaceful atmosphere and convenient location. With extensive updates already completed, this home is ready for its next owner to move in and enjoy. Schedule your private showing today!

840 Thunderbird Dr, Florence

Listing courtesy of Listing Agent: Alexis Marino (Office: 843-358-5263) from Listing Office: Coastal Land & Home.
2215 McLaurin Rd., Florence
$475,000
4 Beds ⋅ 4 Baths ⋅ 2617429 MLS
Welcome to 2215 McLaurin Dr, Florence, SC 29501, an exceptional residence designed for both luxurious daily living and grand-scale entertaining. From the striking architectural details to the resort-style backyard, every inch of this home exudes quality and thoughtful functionality. The heart of the home is a breathtaking Great Room defined by a dramatic 31-foot A-frame ceiling, creating an expansive and airy atmosphere. This space flows effortlessly into a dedicated dining area, perfect for hosting large gatherings. Double glass doors transition into a sun-drenched sunroom, which features a beautiful arched ceiling, five large windows, and dual exit doors leading to the outdoor oasis. A conveniently located half-bath serves this main living zone. The gourmet chef's kitchen is a masterpiece of efficiency and style, anchored by 40-inch tall cabinetry that maximizes storage. Premium details include hidden trash receptacles, rotating lazy Susan corner shelves, and large pull-out drawers. The space is fully equipped with high-end stainless steel appliances, including a KitchenAid gas range with a convection oven and a premium Frigidaire Gallery three-door refrigerator. Escape to the private master bedroom suite, characterized by an elegant dropped ceiling and an oversized wrap-around walk-in closet. The attached en-suite bathroom boasts timeless ceramic walls and flooring, a massive 5x5 walk-in shower, a dual-sink vanity, a linen closet, and a private enclosed toilet room. The home offers a highly functional layout for family or guests. The rear bedroom features two large windows and a vented, double-door walk-in closet, connecting seamlessly to a Jack-and-Jill bathroom where each flanking bedroom enjoys its own private vanity sink and linen closet. Two additional front bedrooms each feature generous walk-in closets, while a dedicated utility hallway houses a convenient laundry area complete with a sink, built-in shelving, and drawers. The outdoor living space is a private resort-style paradise designed for ultimate relaxation. The centerpiece is a stunning 23' x 33' in-ground swimming pool featuring integrated water fountains and vibrant underwater night lighting. You can lounge on the heated tanning deck or the massive 77' x 22' concrete pool deck. The expansive backyard also includes a 9' x 20' multi-level deck leading to a substantial 14' x 32' storage building, offering endless possibilities for a workshop, studio, or pool house.

2215 McLaurin Rd., Florence

Listing courtesy of Listing Agent: Ann King () from Listing Office: Brand Name Real EstateFlorence.
706 Poor Farm Rd., Effingham
$210,000
4 Beds ⋅ 3 Baths ⋅ 2616686 MLS
Welcome to this spacious story-and-a-half Cape Cod–style home offering over 3,300 sqft of flexible living space on a 1.1-acre lot. Featuring 3 bedrooms with the potential to convert additional rooms into up to 6 bedrooms, this property is ideal for growing families or anyone needing extra room. The home includes 2.5 bathrooms, plus a third full bathroom that is ready for your personal updates and finishing touches. Major improvements include updated windows in 2022 and a new heat pump installed in 2024. Enjoy a large eat-in kitchen, a generous walk-in pantry, and an additional storage area conveniently located near the kitchen. Outside, an old barn provides extra storage or workshop possibilities. This home is filled with opportunity and ready for you to make it your own.

706 Poor Farm Rd., Effingham

Listing courtesy of Listing Agent: Stacy Strickland () from Listing Office: Carolina Realty & Associates.
815 Sheila Dr., Johnsonville
$389,900
4 Beds ⋅ 2 Baths ⋅ 2615741 MLS
This incredible, beautiful home only one year old nicely placed on a brick foundation and is perfectly situated on 8.35 acres and surrounded by woods on two sides, offering the ideal blend of privacy, nature, and modern luxury. The attractive exterior features cedar shakes accents, double concrete patios in the front and back, decorative black iron railings and storm glass doors that create an impressive first impression. Step inside to discover beautiful luxury LVP flooring that flows throughout the spacious open floor plan, seamlessly connecting the living room, formal dining room, and kitchen areas. The stunning Dove White kitchen is designed for both beauty and functionality, featuring a huge center island with breakfast bar and stainless farmhouse sink, abundant cabinetry, built-in desk area, decorative range hood above the smooth-top Frigidaire range, LG stainless refrigerator, Frigidaire dishwasher, subway tile backsplash, pantry, recessed lighting, pendant lights, and double arch windows that fill the space with natural light. The formal dining room showcases a tray ceiling and crown molding, while an additional bonus area offers a perfect second living area complete with double windows, chair rail molding, and ceiling fan for added comfort. The spacious owner's suite offers two walk-in closets, a ceiling fan, and elegant French doors with glass accents leading to the luxurious bath featuring double vanities, a makeup station with additional cabinetry, a soaking tub surrounded by storage cabinets, and a large tiled walk-in shower with dual shower heads. Outside you'll appreciate the impressive 45x30 three-bay metal building with concrete floors and electricity. The first bay offers a 9-foot entrance, the second bay a 12-foot entrance and the third bay serves as an open entertainment area. Additional amenities include an invisible fence, camper hookup, generator, 50-amp service pole, a 30-foot private well, fishpond, and an abundance of fruit and nut trees including pear, apple, peach, pawpaw, grape vines, and black walnut trees. If you're looking for privacy, room to roam, an area for gardening, room for a horse or chickens or goats and a peaceful setting and all the beauty of nature than you have found the perfect spot. Only 7 mins out of Johnsonville, 9 mins from Hemingway, 42 mins from Georgetown, 43 mins from Conway and 48 mins from Florence.

815 Sheila Dr., Johnsonville

Listing courtesy of Listing Agent: Gracen Cagle (Cell: 843-833-0722) from Listing Office: The Litchfield Company Real Estate.
Start Your Search

Provided courtesy of The Coastal Carolinas Association of REALTORS®. Information Deemed Reliable but Not Guaranteed. Copyright 2026 of the Coastal Carolinas Association of REALTORS® MLS. All rights reserved. Information is provided exclusively for consumers’ personal, non-commercial use, that it may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.

How much is your home worth?

Get instant property value now!